Using Multicolor Flow Cytometry for COVID-19 Research

Designing multicolor flow cytometry panels to characterize immunological changes observed in COVID-19 patients

The COVID-19 pandemic underscores a need to understand the biological mechanisms underlying disease progression and severity. Early studies reported a correlation between immune response dysfunction and disease severity in COVID-19 patients. A deeper understanding of how SARS-CoV-2 interacts with the host immune system is required to better understand COVID-19 pathogenesis and identify biomarkers that scientists could use to predict, monitor, and prevent COVID-19 progression. Flow cytometry, which is routinely used to assess immunophenotypic and functional changes in response to viral infection, plays a critical role in COVID-19 research due to its ability to simultaneously measure the expression of multiple proteins at the single-cell level.

Download this ebook from BD Biosciences to learn

  • Protocols and best practices for preparing cells for flow cytometry
  • How multicolor flow cytometry panels can be used to study cell types of interest in COVID-19