Undruggable

Welcome to Undruggable, a special edition podcast series produced by The Scientist’s Creative Services Team.

This series is brought to you by Amgen, a pioneer in the science of using living cells to make biologic medicines. They helped invent the processes and tools that built the global biotech industry, and have since reached millions of patients suffering from serious illnesses around the world with their medicines.

Beginning with the introduction of aspirin at the start of the 20th century, there have been three major waves of innovation in drug discovery. While breakthrough discoveries have been made, 85% of disease targets are still considered undruggable, which represents an ongoing barrier to discovering medicines for complex diseases like cancer and autoimmune conditions. Ray Deshaies, who has spent decades in academic research and is a senior vice president at Amgen, believes that the fourth wave of innovation is here, led by new types of multispecific medicines that will radically alter our concept of how drugs can work and pave the way for new solutions.

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Episode 1 - The Next Wave of Drug Development
October 21, 2021
Episode 2 - Drugging the Undruggable: The Biology of PROTACs
October 28, 2021
Episode 3 - Discovery at the DNA Encoded Library
November 4, 2021
Episode 4 - The Emerging Induced Proximity Toolkit
November 11, 2021
Episode 5 - Induced Proximity for Cancer and Beyond
November 18, 2021

Visit this page to sign up for the Undruggable Q&A series, airing soon!

Webinar 1 - The Next Wave of Drug Development and Drugging the Undruggable: The Biology of PROTACs
November 3, 2021
Webinar 2 - Discovery at the DNA Encoded Library
November 10, 2021
Webinar 3 - The Emerging Induced Proximity Toolkit
November 17, 2021

Undruggable - A special 5-part podcast series

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