Cancer Immunotherapy: CRISPR Reveals Targets In Vivo

While T cell immunotherapies effectively battle certain cancers, many cancers do not respond to these treatments. To find solutions to this problem, researchers use modern genetic techniques, such as genome-wide CRISPR-based screens, to enhance the anti-cancer immune response and increase cancer cell susceptibility to treatment. Niki Spahich from The Scientist’s Creative Services team spoke with Sidi Chen, assistant professor of genetics and synthetic biology at Yale University, to learn more.

The Scientist Speaks is a podcast produced by The Scientist’s Creative Services team. Our podcast is by scientists and for scientists. Once a month, we will bring you the stories behind news-worthy molecular biology research. This month's episode is sponsored by 10x Genomics.


Sidi Chen, PhD
Assistant Professor
Department of Genetics and
Synthetic Biology Institute

Yale University



10x Genomics builds solutions to interrogate biological systems at a resolution and scale that matches the complexity of biology. Their rapidly expanding suite of products, which include instruments, consumables, and software, has enabled customers to make fundamental discoveries across multiple research areas, including cancer, immunology, and neuroscience.

Listen Now


Information you provide will be held in confidence and will be shared with the sponsoring vendor(s) of this podcast. We may use the information to contact you about your account and to let you know about related programs and products; you may opt-out at any time. This allows The Scientist to keep these podcasts free of charge for our readers.