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Event Overview

Progress towards the development of effective therapies for brain disorders is held back by a lack of understanding of pathological mechanisms. However, our understanding has been vastly improved by recent advances in systems biology: genomics, epigenomics, transcriptomics, proteomics, and metabolomics. Advances in metabolomics for example has demonstrated the complexity of Alzheimer’s Disease (AD) and other neurodegenerative conditions, as well as underscored the challenges in developing efficacious therapies. By defining systems-level mechanisms in neurodegenerative disease, insights into disease mechanisms can be garnered, biomarker panels can be advanced, and individualized medicine can be developed. The Scientist is bringing together a panel of experts to present their work and provide insight into the use of -omics in investigating neurological disorders.

Topics to be Covered
  • Integrative proteomics for novel target and biomarker discovery in Alzheimer’s Disease
  • The application of metabolomics for biomarker discovery in Alzheimer's Disease
Wednesday, February 27, 2019
2:30 - 4:00 PM Eastern Time


Nicolas Seyfried, PhD
Nicholas Seyfried, PhD
Associate Professor, Depts. of Biochemistry & Neurology
Emory School of Medicine

Eugenia Trushina, PhD
Eugenia Trushina, PhD
Associate Professor, Depts. of Neurology & Pharmacology,
Director, Mitochondrial Neurobiology & Therapeutics Laboratory
Mayo Clinic

Bryen A Jordan

Bryen A. Jordan, PhD

Associate Professor, Dept. of Neuroscience
Albert Einstein College of Medicine
Dominick P. Purpura Department of Neuroscience

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-Omics for Brain Disorders

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