Hijacking Genes: Uncovering the Cause of Lineage Ambiguous Leukemia

Childhood cancer is devastating. Every year over 15,000 children in the United States are diagnosed with cancer, with leukemia accounting for 28 percent of all childhood cancers in children under the age of 15. Leukemia, however, is not a single class of cancer. There are numerous forms of leukemia each with its own distinct cause.

In this episode, Tiffany Garbutt from The Scientist’s Creative Services team spoke with Charles Mullighan, member of the department of pathology and deputy director of the Comprehensive Cancer Center at St. Jude Children’s Research Hospital, about the search for the molecular drivers underlying lineage ambiguous leukemias, a diverse subclass of leukemias with unknown origins.

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LabTalk is a special edition podcast produced by The Scientist's Creative Services Team, where we explore topics at the leading edge of innovative research. This month’s episode is sponsored by 10x Genomics.




Charles G. Mullighan, MBBS (Hons), MSc, MD
Member, St. Jude Faculty
Deputy Director, Comprehensive Cancer Center
Co-leader, Hematological Malignancies Program
Medical Director, St. Jude Biorepository
William E. Evans Endowed Chair
St. Jude Children’s Research Hospital



This episode is brought to you by 10x Genomics, which builds solutions for interrogating biological systems at a resolution and scale that matches the complexity of biology. Their rapidly expanding suite of products, which includes instruments, consumables, and software, enables fundamental discoveries across multiple research areas, including cancer, immunology, and neuroscience.

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