The Epigenetic Origins of Allergy and Asthma

Since the 1950s, there has been a rapid rise in the incidence of allergic diseases, particularly in western countries. Experts agree that the rapid increase in cases is not due to increased awareness, and the genetics behind allergies have not changed. But the environment has changed. Genetic predisposition affects the likelihood of developing allergies, but the environment acts on genetic background.

In this month’s episode, we discuss the epigenetic origins of allergies and asthma and explore the environmental exposures that affect our generation and the next. Tiffany Garbutt from The Scientist’s Creative Services team spoke with John Holloway, professor of allergy and respiratory genetics and associate dean of research at the University of Southampton, to learn more.

The Scientist Speaks is a podcast produced by The Scientist’s Creative Services team. Our podcast is by scientists and for scientists. Once a month, we bring you the stories behind news-worthy molecular biology research.


John Holloway, PhD
Professor of Allergy and Respiratory Genetics
Associate Dean of Research
University of Southampton

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